C7850-18B1
Complement Component 4c (Complement C4c, C4c)
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£761.00
- SKU:
- C7850-18B1
- Reinheit:
- Purified by Protein A affinity chromatography from ascites.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Purified human Complement Component 4c.
- Klon:
- 10B395 (10-12)
- Format:
- Supplied as a liquid in borate buffered saline, 0.09% sodium azide.
- Weitere Details:
- The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b’s alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two achain fragments, alpha 4 (13kD) and alpha 3 (25kD) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma. Applications: Suitable for use in ELISA, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Histology Positive Control Tissue: Kidney sections from post-streptococcal glomerulonephritis patients Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice