C7510-50L
Collagen Type IV (Arresten, ASLN, ATS, CA54, Canstatin, COL4A1, COL4A2, Collagen Alpha 1(IV) Chain, Collagen Alpha 2(IV) Chain, Collagen IV Alpha 1 Polypeptide, Collagen IV Alpha 2 Polypeptide, Collagen of Basement Membrane Alpha 1 Chain, Collagen of Basement Membrane Alpha 2 Chain, Collagen Type IV Alpha 1, Collagen Type IV Alpha 2, Goodpasture Antigen)
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£927.00
- SKU:
- C7510-50L
- Reinheit:
- Purified. ≥95% by SDS-PAGE.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Human glomeruli
- Klon:
- 2Q645 (24.12.8 (PHM-12))
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
- Weitere Details:
- Collagen IV antibody may be useful for the demonstration of basal lamina in invasive epithelial tumors. This antibody may be used to distinguish benighn glandular proliferations from well differentiated carcinomas. Human plasma proteins do not interfere with collagen binding. Collagen is located in the extracellular matrix of connective tissues. It is part of the interacting network of proteoglycans and proteins that provides a structural framework for both soft and calcified connective tissues. Type IV collagen forms a two-dimensional reticulum and is a major component of the basal lamina. Applications: Suitable for use in Indirect Immunoperoxidase Staining, Immunohistochemistry and ELISA. Provides a marker for an antigen known to be important in glomerular cell-matrix interactions, and should prove useful in research into the mechanisms involved in renal pathology. Other applications not tested. Recommended Dilutions: Indirect Immunoperoxidase Staining: >1:40 Immunohistochemistry: Frozen and protease digested paraffin processed tissue. Optimal dilution determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice