C2581-01D-BIOTIN
CDR2 (Cerebellar Degeneration-related Protein 2, Paraneoplastic Cerebellar Degeneration-associated Antigen, Major Yo Paraneoplastic Antigen, PCD17) (Biotin)
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£927.00
- SKU:
- C2581-01D-BIOTIN
- Reinheit:
- Purified.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- CDR2 (NP_001793, 296-405aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
- Klon:
- 4F5
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
- Weitere Details:
- CDR2 (Cerebellar degeneration related protein 2) is an onconeuronal antigen; i.e. an antigen that is expressed by systemic tumors and elicits an immune response that may develop into an autoimmune neuronal degeneration. Paraneoplastic cerebellar degeneration (PCD) is a disorder in which breast or ovarian tumors express CDR2, which normally is expressed in cerebellar Purkinje neurons. Patients with PCD carry a characteristic antibody called anti-Yo. Anti-Yo sera reacts with at least 2 antigens, a major species CDR2, and a minor species CDR1. Applications: Suitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice