C2548-84N1X
CD154 (CD40 Ligand, Cd40l, CD40-L, Cd40lg, sCD40L, HIGM1, IGM, IMD3, Ly62, Ly-62, T-BAM, T-cell Antigen Gp39, TNF-related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, Tnfsf5) (Azide Free)
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£550.00
- SKU:
- C2548-84N1X
- Reinheit:
- Purified.
- Lagerbedingungen:
- 4°C Do not freeze
- Hersteller:
- United States Biological
- Host:
- Hamster
- Immunogen:
- Activated mouse Th1 clone D1.6.
- Klon:
- MR1
- Format:
- Supplied as a liquid in PBS. No preservative added. Low endotoxin.
- Weitere Details:
- CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands.(1-7) It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporinsensitive.(6) Binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and in vivo and in vitro blockage of CD154 function. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice