C2448-07

CD117 (c-kit, Stem Cell Factor, SCF Receptor, Steel Factor Receptor, Mast Cell Growth Factor, MGF)

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£850.00

SKU:: C2448-07
Reinheit:: Purified by Protein A affinity chromatography from ascites
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant human extracellular c-kit fragment. Epitope: Extracellular second N-terminus Ig-like domain of c-kit. Cellular Localization: Cell membrane/cytoplasmic
Klon:: 0.N.183
Format:: Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Weitere Details:: CD117 or c-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). It is expressed in many tissues and cells. C-kit/SCf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells Applications: Suitable for use in Immunofluorescence and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Frozen or fixed in methacarn or Stieves and embedded in paraffin Optimal dilutions to be determined by the researcher. Positive Control: Skin, GI Stromal tumor (GIST) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.