C2443-86L
CD98 (4F2 Cell Surface Antigen Heavy Chain, 4F2 Heavy Chain Antigen, 4F2hc, 4T2HC, CD98 Heavy Chain, CD98HC, Lymphocyte Activation Antigen 4F2 Large Subunit, MDU1, Monoclonal 44D7, NACAE, Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport) Member 2, SLC3A2)
Größe
£601.00
- SKU:
- C2443-86L
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- RAJI human Burkitt's lymphoma cell line
- Klon:
- MEM-108
- Format:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
- Weitere Details:
- CD98 is a 125kD disulfide-linked heterodimer (80kD glycosylated heavy chain + 45kD non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets. CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 4ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml using human liver Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice