C2443-86E
CD98 (APC)
Größe
£863.00
- SKU:
- C2443-86E
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified by Protein G affinity chromatography.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- CHO celll derived recombinant protein corresponding to Asp105-Gln529 from human CD98.
- Klon:
- 9L811
- Format:
- Supplied as a liquid in saline, 0.09% sodium azide, 0.5% BSA. Labeled with Allophycocyanin (APC).
- Weitere Details:
- CD98, also known as 4F2, is a widely expressed disulfide-linked heterodimer in the solute transporter family. It consists of an 85kD glycosylated type II transmembrane heavy chain and a 40-50kD non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and aa transport function of the light chains. CD98 also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes. Within the extracellular region, human CD98 heavy chain shares 73% and 71% aa sequence identity with mouse and rat CD98 heavy chain, respectively. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels 1-2.5 x 10e5 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Versandbedingungen:
- Blue Ice