C2438-01X
CD86 (Activation B7-2 Antigen, B70, B7-2, BU63, CD28LG2, CTLA-4 Counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte Activation Antigen CD86 Precursor) (Azide Free)
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£499.00
- SKU:
- C2438-01X
- Reinheit:
- Purified
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rat
- Klon:
- 2D10
- Format:
- Supplied as a liquid in PBS. No preservative added.
- Weitere Details:
- CD86 is the B7-2 costimulatory molecule and a ligand for CD28 and CD152. CD86/B7-2 is an 80kD type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80/B7-1, CD86 participates in T cell costimulation via interaction with CD28 and CD152/CTLA-4. It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes and dendritic cells. Since CD86/B7-2 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.1-9 Applications: • Identification and enumeration of CD86+ cells by flow cytometry 1, 3, 4, 9 • Identification of CD86+ cells in frozen sections 8, 9 • Immunoprecipitation 3 • In vivo and in vitro blocking assays 1, 2, 8, 9 Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice