C2418-03C
CD63 (CD63 Antigen, Granulophysin, Lysosome-associated Membrane Glycoprotein 3, LAMP-3, ME491, Melanoma 1 Antigen, MLA1, Melanoma-associated Antigen ME491, Ocular Melanoma-associated Antigen, OMA81H, Tetraspanin-30, TSPAN30, Tspan-30)
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£544.00
- SKU:
- C2418-03C
- Reinheit:
- Purified by Protein G affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- HPB-ALL T cell line
- Klon:
- MEM-259
- Format:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
- Weitere Details:
- The CD63 antigen (Melanoma 1 antigen) is a glycoprotein of 40-60kD belonging to the tetraspans family (TM4SF). CD63 is intracellular lysosomal/endosomal/granule protein that is translocated to cell surface upon activation of platelets, endothelial cells, and granulocytes (activation marker). CD63 is also expressed on monocytes/macrophages and endothelium. Its cellular function has not been exactly elucidated. CD63 is thought to be associated with the early stages of melanoma tumor progression (in regulation of motility and adhesion of melanoma cells). Applications: Suitable for use in Flow Cytometry, Immunocytochemistry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 2ug/ml. Positive material: activated platelets, neutrophils and basophils. Immunohistochemistry (paraffin sections): 10ug/ml. Positive tissue: spleen. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice