C2388-01R4

CD36 (CD36 Antigen, Fatty Acid Translocase, FAT, Glycoprotein IIIb, gpIIIb, gp3b, gpIV, gp4, Leukocyte Differentiation Antigen CD36, PAS-4 Protein, PAS-IV, PASIV, Platelet Collagen Receptor, Platelet Glycoprotein 4, Platelet Glycoprotein IV, Scarb3, Thrombospondin Receptor) (PE)

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£704.00

SKU:: C2388-01R4
Anwendung:: Flow Cytometry
Reinheit:: Purified by Protein G affinity chromatography from tissue culture supernatant.
Lagerbedingungen:: 4°C Do Not Freeze
Hersteller:: United States Biological
Host:: Rat
Immunogen:: IL-4 treated mouse thioglycollate-elicited peritoneal macrophages.
Klon:: 9E27 (MF3)
Format:: Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 5% sucrose, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O. Labeled with R-Phycoerythrin (PE).
Weitere Details:: CD36 is an 85kD transmembrane glycoprotein which is primarily expressed on platelets, monocytes/ macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/ aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat; 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Hybridoma: Y3Ag 1.2.3 myeloma cells with spleen cells from DA rats Storage and Stability: Store product at 4°C before and after reconstitution. DO NOT FREEZE! Lyophilized and reconstituted products are stable for 12 months at 4°C after receipt. Reconstitute lyophilized powder with sterile ddH2O prior to use and store remainder as an undiluted liquid. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product centrifuge the original vial prior to removing the cap.

Versandbedingungen:: Blue Ice