C2380-08G

CD28

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£406.00

SKU:: C2380-08G
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Hamster
Immunogen:: Purified from mouse C57BL/6N corresponding to T cell lymphoma EL4 cell line.
Klon:: 5K12 (PV-1)
Format:: Supplied as a liquid in 100mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added.
Weitere Details:: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation.1-4 CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells.5 CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.6-9 Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and In-vitro costimulation of T cells and NK cells. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.