C2276-10X
CD25 (Tac antigen, p55, Interleukin 2 Receptor alpha, IL2Ra, T Cell Growth Factor Receptor) (BSA & Azide Free)
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£820.00
- SKU:
- C2276-10X
- Reinheit:
- Purified by Protein G affinity chromatography from ascites.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human interleukin-2 receptor. Cellular Localization: Cell membrane
- Klon:
- 0.N.93 (IL2R.1)
- Format:
- Supplied as a liquid in PBS, pH 7.4. Also available with BSA and azide. See C2276-10.
- Weitere Details:
- CD25, otherwise known as the Tac antigen or p55, is the alpha chain of the Interleukin-2 (IL-2) receptor. The IL-2 receptor is expressed on activated cells including T cells, B cells and monocytes. It is also present on a subset of thymocytes, HTLV-1 transformed T and B cells, EBV transformed B cells, myeloid precursors and oligodendrocytes. IL-2 induces the expression of the CD25 subunit on NK cells. The IL-2 receptor consists of at least three distinct membrane components: the alpha chain (IL-2R-alpa, Tac, CD25), the beta chain (IL-2R-beta, p75, CD122), and the gamma chain (IL-2R-gamma). CD25 is undetectable on resting T cells but is induced upon T-cell activation. Applications: Suitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Tonsil or lymph node. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice