C2265-49B
CD14 (CD14 Antigen, CD14 Molecule, Monocyte Differentiation Antigen 14, Myeloid Cell Specific Leucine Rich Glycoprotein)
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£576.00
- SKU:
- C2265-49B
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
- Klon:
- MEM-15
- Format:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
- Weitere Details:
- The CD14 molecule has been reported to be involved in the endotoxin mediated release of Tumor Necrosis Factor alpha by monocytic cells (see S.D. Wright et al.). Inhibits the endotoxin induced release of TNF by monocytes because it blocks the binding of LPS-LBP to monocytes. CD14 is present on most monocytic and macrophage like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is present in low density on a subpopulation granulocytes and activated or transformed B-cells. The antibody reacts with both soluble and monocyte surface CD14. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice