C2262-43E
CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor) (APC)
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£448.00
- SKU:
- C2262-43E
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Rat
- Immunogen:
- B10 mouse spleen cells enriched for T cells
- Klon:
- M1/70
- Format:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide Labeled with Allophycocyanin (APC).
- Weitere Details:
- CD11b (integrin alphaM subunit) is a 165-170kD type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1ug/ml Optimal dilutions to be determined by the researcher. Excitation Laser: Red (633nm) Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Versandbedingungen:
- Blue Ice