C2259
CD8 (Leu2 T lymphocyte antigen, MAL, OKT8 T Cell antigen, p32, T cell antigen Leu2, T cell surface glycoprotein CD8 alpha, Suppressor/Cytotoxic T cell)
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£1,292.00
- SKU:
- C2259
- Anwendung:
- IHC-Fr
- Reinheit:
- Tissue culture supernatant
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to 13aa from the C-terminal cytoplasmic domain of the alpha chain of human CD8. Cellular Localization: Cell membrane
- Klon:
- 0.N.66 (C8/144B)
- Format:
- Supplied as a liquid, 0.09% sodium azide.
- Weitere Details:
- CD8 molecule consists of two chains, termed a and B chain, which are expressed as a disulphide-a b heterdimer or as an alpha a homodimer on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8+ Tcells expresses CD8 as abheterodimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 a chain (but not B chain). Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Formalin/paraffin): 1:25-1:50 for 20 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilutions to be determined by the researcher. Hybridoma: p3-NS1/AG4.1 myeloma cells with spleen cells from Balb/c mice. Positive Control: Lymph node or tonsil Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice