CTNNG (Junction Plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, DP3)

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£642.00

SKU:: C2069-60D
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-GLRPPYPTADHMLA, from human CTNNG at C-terminal. Species Sequence Homology: canine and porcine
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:: JUP is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating aa motif called the armadillo repeat. Applications: Suitable for use in Peptide ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:32,000 Western Blot: 0.1-0.3ug/ml shows 80kD band observed in lysates of cell lines A431 and NIH3T3 and in rat eye lysates Immunohistochemistry (paraffin): 5ug/ml using human heart. Requires HIER using sodium citrate buffer pH6.0 prior to staining. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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