C1036-02L
Calreticulin, aa18-417, Recombinant, Human (CALR, Calregulin, cC1qR, CRP55, CRTC, Endoplasmic Reticulum Resident Protein 60, ERp60, FLJ26680, grp60, HACBP, Sicca Syndrome Antigen A, SSA, Ro, Autoantigen Ro)
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£576.00
- SKU:
- C1036-02L
- Anwendung:
- WB
- Molekulargewicht:
- 48.7
- Reinheit:
- ~85% by SDS-PAGE. Purified by using conventional chromatography techniques.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Supplied as a liquid in 20mM Tris HCl, pH 8.0, 1mM DTT, 0.1M sodium chloride, 10% glycerol.
- Weitere Details:
- Calreticulin is the major calcium binding protein found in smooth muscle sarcoplasmic reticulum (SR) and non-muscle endoplasmic reticulum (ER) membranes. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, Calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. Recombinant human Calreticulin protein, fused to His-tag at N-terminus, was expressed in E. coli. Also available DTT-Free. See C1036-02L1 Recombinant protein corresponding to aa18-417 of human Calreticulin 6x His tagged expressed in E. coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEPAVYFKEQ FLDGDGWTSR WIESKHKSDF GKFVLSSGKF YGDEEKDKGL QTSQDARFYA LSASFEPFSN KGQTLVVQFT VKHEQNIDCG GGYVKLFPNS LDQTDMHGDS EYNIMFGPDI CGPGTKKVHV IFNYKGKNVL INKDIRCKDD EFTHLYTLIV RPDNTYEVKI DNSQVESGSL EDDWDFLPPK KIKDPDASKP EDWDERAKID DPTDSKPEDW DKPEHIPDPD AKKPEDWDEE MDGEWEPPVI QNPEYKGEWK PRQIDNPDYK GTWIHPEIDN PEYSPDPSIY AYDNFGVLGL DLWQVKSGTI FDNFLITNDE AYAEEFGNET WGVTKAAEKQ MKDKQDEEQR LKEEEEDKKR KEEEEAEDKE DDEDKDEDEE DEEDKEEDEE EDVPGQAKDE L Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice