C0115-01D-HRP

Calcitonin Gene Related Peptide (CGRP, Calcitonin Gene-related Peptide 1, CGRP1, Calcitonin Gene-related Peptide I, CGRP I, CGRP-I, Alpha Type CGRP, CAL6, Cal1, Calc, Calcitonin 1, CALC 1, CALC 2, RATCAL6, Calcitonin-related Polypeptide alpha, CALC A, CALCA) (HRP)

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£882.00

SKU:: C0115-01D-HRP
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to aa23-37 of rat Tyr-CGRP conjugated to gamma globulin.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Weitere Details:: CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed. Applications: Suitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Not recommended for resin sections. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Paraffin and frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Versandbedingungen:: Blue Ice