B0003-61B

BCL2L2 (Bcl-w, Bcl-2-like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCLW, KIAA0271

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£760.00

SKU:: B0003-61B
Reinheit:: Purified by Protein G affinity chromatography from hybridoma culture supernatant. Endotoxin: ≤0.1EU/ug (LAL).
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to Met1-Thr172 from human Bcl-w, expressed in E.coli.
Klon:: 12K13
Format:: Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul of PBS.
Weitere Details:: Bcl-w is a pro-survival (apoptotic) member of the Bcl-2 family; a family involved in the regulation of cellular apoptosis at the mitochondrion. Relative to its Bcl-2 counterparts there is considerably less data on this prticular protein. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Applications: Suitable for use in Neutralization. Other applications not tested. Recommended Dilution: Neutralization: 10ug to neutralize 1ug Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.