B0002-92E9

BACE2, ID (Beta-secretase 2, Beta-site Amyloid Precursor Protein Cleaving Enzyme 2, Beta-site APP Cleaving Enzyme 2, Aspartyl Protease 1, Asp 1, ASP1, Membrane-associated Aspartic Protease 1, Memapsin-1, Aspartic-like Protease 56kD, Down Region Aspartic Protease, DRAP, Theta-secretase, AEPLC, ALP56, ASP21, CDA13, UNQ418/PRO852)

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£696.00

SKU:: B0002-92E9
Reinheit:: Purified by ammonium sulfate precipitation
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the center region of human BACE2 (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Applications: Suitable for use in ELISA, Western Blot, and Indirect Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 1:100-1:500 ELISA: 1:1,000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.