A4190-17C-FITC
Aurora C (Serine/threonine-protein kinase 13, Serine/threonine kinase AIE2, Aurora IPL1/Eg2 protein 2, Aurora IPL1-related kinase 3) (FITC)
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£1,042.00
- SKU:
- A4190-17C-FITC
- Anwendung:
- WB
- Reinheit:
- Purified by immunoaffinity chromatography
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide derived from an internal region of the human Aurora C (Serine/threonine-protein kinase 13, Serine/threonine kinase AIE2, Aurora/IPL1/Eg2 protein 2, Aurora/IPL1-related kinase 3) protein.
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Fluorescein isothiocyanate (FITC).
- Weitere Details:
- Aurora C1 is a member of the aurora/Ipl1p family of protein kinases that are important regulators of mitosis.2 Aurora C is a novel chromosomal passenger protein that, in coordination with Aurora B, regulates mitotic chromosome dynamics in human cells.3,4 Aurora C may play a role in organizing microtubules relating to the function of the centrosome/spindle pole during mitosis, and is localized to the centrosome from anaphase to cytokinesis.5 The expression of Aurora C is maximum at M phase.5 Aurora C is activated by directly associating with inner centromere protein (INCENP).3 Aurora C is expressed in normal testis6, and elevated expression levels are seen in a subset of cancer cells such as HepG2 and HeLa cells.5 Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Human placenta homogenates, and human JEG3, HEPG2, HeLa, HEK293, NGP96, SKNEP-1 and U251 cell lysates. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice