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A2299-85

Apoptolidin

Größe

£464.00

SKU:
A2299-85
Molekulargewicht:
1129.37
Reinheit:
>95% by HPLC
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
CAS Number:
194874-06-1
Weitere Details:
Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene at an IC50 = 11 ng/ml. It is among the most selective cytotoxic agents tested by the NCI in human cancer cell lines. Although the apoptotic activity of apoptolidin correlates with F0F1-ATPase inhibition, recent evidence suggests the existence of a secondary biological target or more complex mode of action. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO Related to: Isoapoptolidin
Versandbedingungen:
Blue Ice