A2299-76V4
APOF (Apolipoprotein F, Apo-F, Lipid Transfer Inhibitor Protein, LTIP)
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£642.00
- SKU:
- A2299-76V4
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-KSYDLDPGAGSLE at the C-terminal of human APOF (NP_001629.1).
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Weitere Details:
- Apolipoprotein F (Apo F), also known as lipid transfer inhibitor protein (LTIP) based on its ability to inhibit lipid transfer between lipoproteins, is a protein component of several lipoprotein classes and a physiologic regulator of cholesteryl ester transfer protein (CETP) function. Apo F activity was reported to be localized to LDL, consistent with its greater inhibitory activity on this lipoprotein. Apo F activity is controlled by its reversible incorporation into an inactive complex which provides for short-term fine-tuning of lipoprotein remodeling mediated by CETP. ApoF overexpression reduces HDL cholesterol levels by increasing clearance of HDL-CE.ApoF may be an important determinant of HDL metabolism and reverse cholesterol transport. Applications: Suitable for use in Peptide ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:32,000 Immunohistochemistry (Paraffin): 2.5-3.8ug/ml Western Blot: 0.3-1ug/ml, observed in human liver lysates on ~35kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice