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A1475-08H

AMPK gamma, ID (5'-AMP-activated Protein Kinase Subunit gamma-1, AMPK Subunit gamma-1, AMPK gamma1, AMPKg, PRKAG1)

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£696.00

SKU:
A1475-08H
Reinheit:
Purified by ammonium sulfate precipitation.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rabbit
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 265-295 in the central region of human PRKAG1. Species Sequence Homology: bovine and porcine.
Format:
Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:
PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice