AG 490 (Tyrphostin B42, N-benzyl-3,4-dihydroxy-benzylidenecyanoacetamide)

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£422.00

SKU:: A0928-65
Reinheit:: ~98%
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 134036-52-5
Format:: Supplied as a brownish yellow solid.
Weitere Details:: Specific and potent JAK2 protein tyrosine kinase inhibitor. Also, inhibits EGF receptor autophosphorylation, with IC50 of 100nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Blocks growth of leukemic cells in vitro and in vivo. Synonyms: N-benzyl-3,4-dihydroxybenzylidenecyanoacetamide CAS No: 134036-52-5 Melting Point: 218-220°C Solubility: Acetone, Chloroform, Ethanol, Methanol Method for Determining Identitiy: H NMR Spectroscopic Analysis TLC Conditions: SiO2; Hexane: Ethyl Acetate; 2:1; Visualized with AMCS; Single Spot; Rf=0.25. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.