Apolizumab (HLA-DRB)

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£749.00

SKU:: 591671
Reinheit:: ≥95%
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Human
Immunogen:: Recombinant protein corresponding to humanized HLA-DRB [Homo sapiens], expressed in CHO cells.
Format:: Supplied as a liquid in PBS, pH 7.5.
Weitere Details:: Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers. Apolizumab is a humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. Applications: Suitable for use in ELISA and SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.