590115
CFTR
Größe
£965.00
- SKU:
- 590115
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to aa258-385 of human CFTR.
- Klon:
- CFTR/1775R
- Format:
- Supplied as a liquid in 1X PBS, 0.1mg/ml BSA, 0.05% sodium azide.
- Weitere Details:
- CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Applications: Suitable for use in Immunohistochemistry and Immunofluorescence.. Other applications not tested. Recommended Dilution: Immunofluorescence: 0.5-1ug/ml Immunohistochemistry(formalin-fixed paraffin sections): 1-2ug/ml for 30 min at RT Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice