TERB1

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£460.00

SKU:: 578746
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa301-550 from human Telomere repeats-binding bouquet formation protein 1.
Format:: Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Weitere Details:: Meiosis-specific telomere-associated protein involved in meiotic telomere clustering, also named bouquet formation, the telomere-mediated chromosomal movement along the nuclear envelope which is crucial for homologous pairing and synapsis. Probably acts as a hub for the assembly of a conserved meiotic telomere complex required for chromosome movements via interaction with TERF1. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.