CD38, Recombinant, Human, aa43-300, His-Tag, (PE)

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£1,015.00

SKU:: 544232
Molekulargewicht:: 31
Reinheit:: ≥90%
Lagerbedingungen:: -70°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 20% glycerol. Labeled with R-Phycoerythrin (PE).
Weitere Details:: CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability; cyclic ADP-ribose, NAADP+ , and ADP-ribose 3. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells 1, 4. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic β cells 5, 6. Source: Recombinant protein corresponding to aa43-300 from human CD38, fused to His-Tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~31kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.