516682
CD80
Größe
£840.00
- SKU:
- 516682
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Human
- Immunogen:
- Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013).
- Klon:
- IDEC-114 (Galiximab) (recomb)
- Format:
- Supplied as a liquid in PBS, 0.02% Proclin 300.
- Weitere Details:
- Recombinant monoclonal antibody to CD80. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody IDEC-114 (Galiximab). CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas. Applications: Suitable for use in Blocking, Immunoprecipitation, Western Blot, ELISA, Flow Cytometry, and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice