Timosaponin A3

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£314.00

SKU:: 467649
Molekulargewicht:: 740.92
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 41059-79-4
Weitere Details:: Timosaponin A3 suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells. Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator. Molecular Formula: C39H64O13 Molecular Weight: 740.92 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.