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464554

Rebastinib

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£409.00

SKU:
464554
Molekulargewicht:
553.59
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
CAS Number:
1020172-07-9
Format:
Supplied as a Off-White Solid
Weitere Details:
Rebastinib shows the selectivity for growth inhibition of Bcr-Abl-positive cells by its marked inhibition of CML cell lines compared to non-CML leukemia lines. Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1. Molecular Formula: C30H28FN7O3 Solubility: Methanol (Slightly) Molecular Weight: 553.59 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Versandbedingungen:
Ambient