Olaparib-d4

Größe

£531.00

SKU:: 461514
Molekulargewicht:: 438.49
Reinheit:: ≥96%
Lagerbedingungen:: 4°C
Hersteller:: United States Biological
CAS Number:: NA
Format:: White to off-white powder
Weitere Details:: Isotope labeled Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy. Potent PARP inhibitor. Synonyms: 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone-d4; AZD 2281-d4; KU 0059436-d4; KU 59436-d4; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine-d4 CAS No: NA Molecular Formula: C₂₄H₁₉D₄FN₄O₃ Molecular Weight: 438.49 Appearance: White to off-white powder Purity: ≥96% Isotopic Purity: ~99% NMR, F NMR, MS: Conforms to reference Solubility: Chloroform (Slightly), DMSO (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.