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457591

N-​[(S)​-​(4-​Nitrophenoxy)​phenoxy-​2,​3,​4,​5,​6-​d5-​phosphinyl]​-​L-​Alanine-d5 1-​Methylethyl Ester

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£685.00

SKU:
457591
Molekulargewicht:
413.37
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
CAS Number:
1874196-88-9
Format:
Supplied as a Pale Yellow Oil
Weitere Details:
N-​[(S)​-​(4-​Nitrophenoxy)​phenoxy-​2,​3,​4,​5,​6-​d5-​phosphinyl]​-​L-​Alanine-d5 1-​Methylethyl Ester is an intermediate in synthesizing PSI-7977-D5 (P839643), an isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Molecular Formula: C18H16D5N2O7P Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Methanol Molecular Weight: 413.37 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Versandbedingungen:
Ambient