456203
Micafungin
Größe
£344.00
- SKU:
- 456203
- Molekulargewicht:
- 1270.27
- Reinheit:
- ≥98%
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- CAS Number:
- 235114-32-6
- Format:
- White to off-white powder
- Weitere Details:
- Micafungin is an antifungal drug that inhibits the production of β-1,3-glucan, an essential component of fungal cell walls. Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. It inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. It received final approval from the U.S. Food and Drug Administration (FDA) on March 16, 2005. Micafungin works by way of concentration-dependent inhibition of 1,3-beta-D-glucan synthase resulting in reduced formation of 1,3-beta-D-glucan, which is an essential polysaccharide comprising one-third of the majority of Candida spp. cell walls. This decreased glucan production leads to osmotic instability and thus cellular lysis. Synonyms: Mycamine; FK463; 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl hydrogen sulfate; 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0 CAS No: 235114-32-6 Molecular Formula: C₅₆H₇₁N₉O₂₃S Molecular Weight: 1270.27 Appearance: White to off-white powder Purity: ≥98% Melting Point: >198ºC (dec.) Solubility: DMSO (Slightly), Methanol (Very Slightly, Heated) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Versandbedingungen:
- Ambient