444080
cDPCP
Größe
£403.00
- SKU:
- 444080
- Molekulargewicht:
- 343.7
- Reinheit:
- ≥95%
- Lagerbedingungen:
- 4°C
- Hersteller:
- United States Biological
- CAS Number:
- 106343-54-8
- Format:
- Yellow solid
- Weitere Details:
- cDPCP is a tumor cell permeable, potent platinum-based antineoplastic agent. It is a cationic monofunctional platinum(II) complex with unique chemical and biological properties. cDPCP binds covalently only to a single DNA base (the N7 atom of a single guanosine residue), and thus forms monofunctional rather than bifunctional lesions with DNA. cDPCP effectively blocks transcription from DNA templates carrying adducts of the complex, unlike DNA lesions of other monofunctional platinum(II) compounds. Synonyms: cis-Diammine(pyridine)chloroplatinum(II) chloride, Pyriplatin, cis-[Pt(NH3)2(py)Cl]+ chloride; (SP-4-2)-Diamminechloro(pyridine)-platinum(1+) Chloride CAS No: 106343-54-8 Molecular Formula: C₅H₁₁ClN₃Pt•Cl Molecular Weight: 343.70 Appearance: Yellow solid Purity: ≥95% Elemental Analysis: (Theoretical) %C: 15.84, %H: 2.92, %N: 11.08 (Actual) %C: 16.02, %H: 2.97, %N: 11.55 NMR: Conforms to Structure MS: Conforms to Structure TLC Conditions: SiO2; Dichloromethane : Methanol = 8 : 2; Visualized with UV and KMnO4; Single Spot, Rf = 0.30._x000B_Elemental Analysis: Melting Point: >240°C (dec.) Chloride: ~11% by Ion Chromatography Solubility: DMSO (Slightly), Water (Slightly) Storage and Stability: Store at 4°C. Hygroscopic, under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Versandbedingungen:
- Ambient