(6R,7R)--[(1Z)-2-(2,4-Dinitrophenyl)ethenyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester

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£735.00

SKU:: 439080
Molekulargewicht:: 636.65
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 828919-20-6
Format:: Supplied as a Dark Red Solid
Weitere Details:: (6R,7R)--[(1Z)-2-(2,4-Dinitrophenyl)ethenyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester is an intermediate in synthesizing Nitrocefin (N493815), a chromogenic β-lactamase substrate that undergoes colour change from yellow to red as the amide bond in the β-Lactam ring is hydrolyzed by β-lactamase. Nitrocefin undergoes colour changes induced by lactamases produced by Gram-positive and Gram-negative bacteria. Several studies have utilized the colour changing properties of Nitrocefin for the detection of β-lactamase activity from bacterial cell extracts by isoelectric focusing and spectroscopy. Nitrocefin has also been used in studies involving β-lactamase resistant antibiotics. Molecular Formula: C29H24N4O9S2 Solubility: Dichloromethane Molecular Weight: 636.65 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.