427727
3'-Methoxy-4',5,7-trihydroxyisoflavone
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£479.00
- SKU:
- 427727
- Molekulargewicht:
- 300.26
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- CAS Number:
- 36190-95-1
- Weitere Details:
- 3'-Methoxy-4',5,7-trihydroxyisoflavone is a derivative of Genistein (G350000); a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. Molecular Formula: C16H12O6 Molecular Weight: 300.26 Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Versandbedingungen:
- Ambient