397016
CD335 (NKp46, Natural Cytotoxicity Triggering Receptor 1, NCR1)
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£576.00
- SKU:
- 397016
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified by Protein A affinity chromatography from tissue culture supernatant.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Fusion protein corresponding to extracellular region of porcine CD335.
- Klon:
- VIV-KM1
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Weitere Details:
- CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor and is involved in the control of viral infection and tumor development. Until recently little has been known about porcine and veterinary NK cells. CD335 is expressed by human natural killer cells and the development of monoclonal antibodies to bovine CD335 and sheep CD335 have enabled researchers to identify and better understand ruminant NK cells. This is the first monoclonal developed to specifically identify porcine CD335 and provides a reagent to facilitate a better understanding of the porcine immune system and aid in the understanding of the role of NK cells in host pathogen defense. Studies using CD335 have shown that, within the porcine, CD335 is not universally expressed by all NK cells and that expression of this marker on NK cells may be influenced by cytokine production. Applications: Suitable for use in Immunofluorescence, Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:200 Optimal dilutions to be determined by the researcher. Hybridoma: SP2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice