MS4A1/CD20, Recombinant, Human, aa210-297, His-Tag (B-Lymphocyte Antigen CD20, MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7)

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£607.00

SKU:: 396908
Molekulargewicht:: 11.1
Reinheit:: ≥90% (SDS-PAGE)
Lagerbedingungen:: 4°C/-20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Weitere Details:: MS4A1, also known as B-lymphocyte antigen CD20, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase and progressively increasing in concentration until maturity. It is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It plays a role in the microenvironmental interactions of B cells. This structurally unique phosphoprotein plays a role in the regulation of human B cell proliferation and differentiation. It was strongly phosphorylated on resting B cells after CDw40 stimulation, suggesting that it may be functionally regulated by a protein kinase. Recombinant human MS4A1, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa210-297 of human MS4A1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~11.1kD (97aa), ~18-28kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADPGIVENEW KRTCSRPKSN IVLLSAEEKK EQTIEIKEEV VGLTETSSQP KNEEDIEIIP IQEEEEEETE TNFPEPPQDQ ESSPIENDSS PHHHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Versandbedingungen:: Blue Ice