KLRB1, Recombinant, Human, aa67-225, hIgG-His-Tag (Killer Cell Lectin-Like Receptor Subfamily B Member 1, KLRB1, CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A, NKRP1A)

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£607.00

SKU:: 396894
Molekulargewicht:: 45.7
Reinheit:: ≥90% (SDS-PAGE)
Lagerbedingungen:: 4°C/-20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Weitere Details:: KLRB1, also known as killer cell lectin-like receptor subfamily B member 1, is classified as a type II membrane protein because it has an external C-terminal. It is expressed by NK cells and may be involved in the regulation of NK cell function. It plays a novel and important role in B cell maturation within the GC in humans. It is expressed by lymphocytes found in human gut and liver, as well as blood, especially natural killer (NK) cells, T helper 17 (Th17) cells, and a population of unconventional T cells known as mucosal-associated invariant T (MAIT) cells. It is also expressed, at intermediate levels, on a prominent subset of polyclonal CD8+ T cells, including antiviral populations that display a memory phenotype. Recombinant human KLRB1, fused to hIgG-His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa67-225 of human KLRB1, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~45.7kD (401aa), ~40-57kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADPQKSSIEK CSVDIQQSRN KTTERPGLLN CPIYWQQLRE KCLLFSHTVN PWNNSLADCS TKESSLLLIR DKDELIHTQN LIRDKAILFW IGLNFSLSEK NWKWINGSFL NSNDLEIRGD AKENSCISIS QTSVYSEYCS TEIRWICQKE LTPVRNKVYP DSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.