Sox2 (ANOP3, Cb236, Delta EF2a, Lcc, Sex Determining Region Y Box 2, SOX 2, Sox2, SOX2 HUMAN, SRY (Sex Determining Region Y) Box 2, SRY Box Containing Gene 2, SRY Related HMG Box 2, SRY Related HMG Box Gene 2, SRY-Box 2, Transcription Factor SOX 2, Transcription Factor SOX-2, Ysb)

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£633.00

SKU:: 381713
Reinheit:: Purified by affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to mouse Sox2.
Klon:: 17J136
Format:: Supplied as a liquid in 0.1M Tris-HCl, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Weitere Details:: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). Applications: Suitable for use in Western Blot, Immunocytochemistry, Indirect Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunocytochemistry: 1:150 Indirect Flow Cytometry:1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice