GADD45 alpha (DDIT 1, DDIT-1, DDIT1, DNA damage Inducible transcript 1, DNA damage-Inducible transcript 1 Protein, GADD45, GADD45A, Growth arrest and DNA damage Inducible 45 alpha, Growth arrest and DNA damage Inducible alpha, Growth arrest and DNA damage-Inducible Protein GADD45 alpha)

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£633.00

SKU:: 381618
Anwendung:: WB
Reinheit:: Purified by affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to GADD45a.
Klon:: 17J57
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.