ULBP1, Recombinant, Human, aa26-216, His-Tag (NKG2D Ligand 1, N2DL-1, NKG2DL1, RAET1I)

Größe

£607.00

SKU:: 377999
Molekulargewicht:: 23.4
Reinheit:: ≥90% (SDS-PAGE)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Weitere Details:: ULBP1, also known as NKG2D ligand 1, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. It is unconventional MHC class I-like molecules exploited by viruses and cancer. Its ligand Methylation contributes to immune system evasion in acute myeloid leukemia. It is independent predictors of good prognosis in cervical cancer. Source: Recombinant protein corresponding to aa26-216 from human ULBP1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~23.4kD (200aa), 28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADLGWVDTHC LCYDFIITPK SRPEPQWCEV QGLVDERPFL HYDCVNHKAK AFASLGKKVN VTKTWEEQTE TLRDVVDFLK GQLLDIQVEN LIPIEPLTLQ ARMSCEHEAH GHGRGSWQFL FNGQKFLLFD SNNRKWTALH PGAKKMTEKW EKNRDVTMFF QKISLGDCKM WLEEFLMYWE QMLDPTKPPS LAPGHHHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.