FPR2 (Formyl Peptide Receptor 2, LXA4R, FPRL1, RFP, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, HM63, LRLP, N-Formyl Peptide Receptor 2, Lipoxin A4 Receptor Like Protein, FMLP-related Receptor I)

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£557.00

SKU:: 369524
Reinheit:: Purified by Protein A and peptide affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: LXA4R, which was first identified based on sequence homology as the formyl peptide receptor like receptor (FPRL1). Lipoxin signaling through the LXA4R inhibits chemotaxis, transmigration, superoxide generation and NF-kappa B activation. Bao et al. (1992) identified 2 structural homologs of formyl peptide receptor (FPR1), FPRL1 (FPR2) and FPRL2 (FPR3). Since these 2 structural homologs did not recognize the ligand FMLP, Bao et al. (1992) referred to them as orphan receptors. Nonetheless, they probably function as chemotactic receptors. Prat et al. (2006) found that a Staphylococcus aureus protein, which they called FLIPr, bound to and impaired neutrophil responses to FPRL1 agonists in terms of calcium mobilization and directed migration. Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.2-2ug/ml. Immunohistochemistry: 5-20ug/ml. Immunocytochemistry: 5-20ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice