AOX1 (Aldehyde Oxidase 1, AO, AOH1, Azaheterocycle Hydroxylase)

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£555.00

SKU:: 369454
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Format:: Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Weitere Details:: Aldehyde oxidase (AO) produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. The human protein was 49% identical to rat XDH and contained several characteristic XDH signature sequences. AOX1 was expressed as a 5.1-kb mRNA predominantly in liver. A 4.5-kb transcript observed in heart, brain, and kidney arose by use of an alternative polyadenylation site.Analysis of a YAC contig revealed that the AOX1 gene is within 280 kb of the D2S116 marker, which is inseparable by recombination from the ALS2 locus. AOX1 is expressed in the ventral horn of the spinal cord, primarily in the glial cells. Based on the tissue localization, linkage data, and the biochemical role of AOX1 in the free radical pathway, these authors suggested that AOX1 is a candidate gene for ALS2. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:5000 Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice