369446
ACOX1 (Acyl Coenzyme A Oxidase 1, Palmitoyl, ACOX, PALMCOX, SCOX, Peroxisomal Acyl-Coenzyme A Oxidase 1, Straight-chain acyl-CoA oxidase)
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£626.00
- SKU:
- 369446
- Anwendung:
- WB
- Reinheit:
- Purified by Protein A and peptide affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- ACOX1 (Arg210~Asn409)
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Weitere Details:
- Peroxisomal acyl-coenzyme A oxidase 1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.The deduced human protein sequence is 89% similar to the rat protein. Like the rat homolog, the human sequence also contains C-terminal ser-lys-leu (SKL) residues which function as a peroxisomal targeting signal. Two mRNA species, 1.9-kb and 2.1-kb, were identified in liver. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice