TBLR1 (F-box-like/WD Repeat-containing Protein TBL1XR1, Nuclear Receptor Corepressor/HDAC3 Complex Subunit TBLR1, TBL1-related Protein 1, Transducin beta-like 1X-related Protein 1, TBL1XR1, IRA1)

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£537.00

SKU:: 369420
Reinheit:: Purified by affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant full length protein corresponding to 514aa of human TBLR1.
Klon:: 17D128
Format:: Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Weitere Details:: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, th ereby allowing cofactor exchange, and transcription activation. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.