369412
Serum Amyloid A Protein (SAA1, Serum Amyloid A-1 Protein, Amyloid Fibril Protein AA)
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£422.00
- SKU:
- 369412
- Reinheit:
- Purified by Protein G affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human Serum amyloid A-1.
- Klon:
- 17D120
- Format:
- Supplied as a liquid in 0.1mol/L sodium chloride, 15mmol/L sodium azide.
- Weitere Details:
- Serum amyloid A protein, also named SAA, Amyloid protein A, Amyloid fibril protein AA, SAA1, SAA2 and PIG4, is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 is produced mainly in the liver and circulates in low levels in the blood. SAA1 may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. The SAA1 cleavage product a designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice