PEG10 (EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3, Retrotransposon-derived Protein PEG10, Embryonal Carcinoma Differentiation-regulated Protein, Mammalian Retrotransposon-derived Protein 2, Myelin Expression Factor 3-like Protein 1, Paternally Expressed Gene 10 Protein, Retrotransposon Gag Domain-containing Protein 3, Retrotransposon-derived Gag-like Polyprotein, Ty3/Gypsy-like Protein)

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£537.00

SKU:: 369396
Reinheit:: Purified by affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to human PEG10 protein fragments expressed in E. coli.
Klon:: 17D104
Format:: Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Weitere Details:: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.